Dr. Elizabeth Komives

Research Area: Structure, function, dynamics and thermodynamics of protein-protein interactions: NMR, mass spectrometry and kinetics.

Dr. Elizabeth Komives is a UCSD Faculty Member and Chair of the Research Scholars. She is responsible for matching each Research Scholar with the appropriate UCSD Faculty Researcher and mentoring the students, which includes meeting with them weekly as a group. Her research interests include understanding the parameters that govern protein-protein recognition and the mechanisms by which these interactions contribute to biological function; the interactions of the LDL-receptor-related protein (LRP-1), which is a 515 kD protein that is responsible for clearing many ligands that are genetically linked to Alzheimer's disease; and a joint effort with the G. Ghosh, A. Hoffmann, P. Wolynes and J. Dyson labs involving understanding the signal transduction mediated by the family of NF-kB transcription factors and their IkB inhibitors.